This study explores the forms of biopolitical management of migrant populations. Central theoretical tools are Michel Foucault’s concept of biopolitics and Giorgio Agamben’s concept of thanatopolitics. In this context, a brief historical review of the management policies of contemporary migration is attempted from a critical perspective. In addition, there are analyzed the new tools for monitoring and recording the migrant population. These are sophisticated techno-scientific systems, according to which the body functions as a basic form of identification and mode of detection, and the subject itself becomes the target and object of mechanisms of power and regulation. In this light, it becomes clear that migratory flows are of great importance on the European agenda, especially after the outbreak of the so-called “refugee crisis” of 2015. Through the example of the establishment and operation of the Refugee and Migrant Accommodation Facilities in Greece, there will be examined the placing thousands of migrants in these facilities as a measure to deal with the 2015 population influx, as well as their transformation into closed facilities, constituting yet another border/ boundary for the refugee population, an enclosed space that facilitates their surveillance and control.